Anxiety and panic

Definition

Anxiety is a feeling of fear and apprehension about a real or perceived threat and may cause excessive worry and heightened tension, affecting important areas of normal functioning (NICE [205]). The source of the feeling may or may not be known (Kennedy Sheldon [144]) and people sometimes refer to it as ‘coming out of the blue’. Different people use different words to describe anxiety, for example ‘stress’, ‘nervousness’ or ‘tension’.
The body has a normal response to fear and stress but, if this response is exaggerated, people might experience a sense of panic. During a panic attack, a number of symptoms can be experienced including palpitations, nausea, trembling, weak legs and dizziness (APA [10]) (Box 5.9). Panic attacks can have a sudden onset and may last 5–20 minutes (MIND [187]). Catastrophic thoughts or images (e.g. having a heart attack, fainting or collapsing) are characteristic of a panic attack and the more frequent and extreme they are the more intense the physiological response becomes (Powell [226]). An indication for many individuals that a panic attack is beginning is a feeling of tightness in the chest or being aware that their breathing is fast. If not managed, this may progress to hyperventilation (Powell [226]).
Box 5.9
Criteria for defining a panic attack according to the Diagnostic and Statistical Manual of Mental Disorders (DSM‐5)
A panic attack consists of a discrete period of intense fear or discomfort in which four or more of the following symptoms develop abruptly and reach a peak within minutes:
  • Palpitations, pounding heart or accelerated heart rate
  • Sweating
  • Trembling or shaking
  • Sensations of shortness of breath or smothering
  • Chest pain or discomfort
  • Feeling of choking
  • Nausea or abdominal distress
  • Feeling dizzy, unsteady, light‐headed or faint
  • Chills or heat sensations
  • Paraesthesias (numbness or tingling sensations)
  • Derealization (feelings of unreality) or depersonalization (being detached from oneself)
  • Fear of losing control or going crazy
  • Fear of dying
Source: Adapted from APA ([10]) with permission of American Psychiatric Publishing.

Anatomy and physiology

Anxious feelings can result in physical symptoms related to the ‘flight or fight’ response as the body responds to the threat, real or otherwise (Figure 5.12). The sympathetic nervous system releases adrenaline and other hormones that lead to:
  • increase in heart rate and therefore palpitations and raised blood pressure
  • faster and shallower breathing (hyperventilation)
  • dizziness
  • dry mouth and difficulty swallowing
  • relaxation of sphincters, leading to an increase in urinary and faecal elimination
  • reduction in blood supply to the intestines, leading to feelings of ‘butterflies’, knotted stomach and nausea
  • increase in perspiration as the body seeks to cool down the tense muscles
  • musculoskeletal pains (particularly in the back and neck) (Powell and Enright [227]).
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Figure 5.12  The body's arousal system during the fight‐or‐flight response. Source: Adapted from Powell ([226]).
These physical symptoms can be perceived as unpleasant by the patient, resulting in further catastrophic worries and an escalation in physical symptoms; in this way, a vicious cycle ensues (Figure 5.13). It is useful to note that although people may feel faint and dizzy when they are anxious, increased blood pressure will ensure they do not actually faint. The exception to this is when someone has a needle phobia and blood pressure initially increases and then drops, which can result in fainting (Jenkins [139]). One hypothesis regarding the reason for the reduction in blood pressure in people with a needle phobia is that it is an adaptive mechanism that minimizes any potential loss of blood and therefore enhances a person's chance of survival.
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Figure 5.13  Example of an anxious spiral.

Related theory

Anxiety is a normal and necessary response to threatening events but can become a problem when it is frequent, exaggerated or experienced out of context (Blake and Ledger [20]). There are a number of theories about anxiety, its causes and how to manage it (Powell and Enright [227]); however, all theories consider the role of the situation as well as the patient's thoughts, emotions, physiology and behaviour. To be effective in supporting and communicating with a patient with anxiety, it is necessary to consider the following components of anxiety:
  • Bodily sensations: as listed above.
  • Thoughts and images: the ideas, memories, beliefs and mental pictures or images the individual has about what might happen in the feared situation (Powell [226]).
  • Behaviour: how the individual behaves when faced with the perceived fear, which often involves avoidance or the adoption of behaviours that increase their sense of safety when they cannot avoid the feared situation or activity. For example, a patient may only attend a hospital appointment with a particular friend, while listening to music or with a book to read. While these behaviours can be helpful in the short term, they can present longer‐term problems, as they reduce the person's ability to believe that they can cope on their own, and the ‘safety behaviour’ may not always be possible. That is, the patient's friend may not be able to accompany them, their music device's battery may run out or they may finish their book.
Within the healthcare context, many patients experience anticipatory anxiety, for example worry and anxiety about future appointments, tests and treatments. Patients are frequently required to have tests or treatments that include needles, which are a common fear. McLenon and Rogers’ ([175]) meta‐analysis found that needle fear and phobia were present in the majority of children, 20–50% of adolescents and approximately 20–30% of young adults; they were less prevalent thereafter.
As levels of anxiety increase, a person's awareness and interaction with the environment can decrease, and recall and general function may be impaired (Kennedy Sheldon [144]). Cognitive functions can be affected due to ‘emotional hijacking’ (Goleman [108]). This occurs when the amount of brain activity in the limbic system (the brain's principal emotional system) increases to a level where it ‘hijacks’, or interferes with, the functions of the pre‐frontal cortex (where most executive functions are processed, such as thinking, reasoning and attention). Conversely, some anxiety and worry can be helpful when they orientate a person's behaviour towards appropriate problem‐solving strategies.

Evidence‐based approaches

Managing generalized anxiety is initially about early recognition and helping people to understand the problem. It is recognized that a person's perception of, or behavioural response to, a situation can exacerbate anxiety. Therefore, it is helpful to provide psychoeducation – that is, an explanation or explanatory model for the development and maintenance of the anxiety (Figures 5.12 and 5.13).
Where possible, it is pertinent to allay the source of anxiety. Nurses have more power than patients in the healthcare setting and may be in a position to help change an anxiety‐provoking situation. Alternatively, they may be able to support patients in thinking through a difficult situation and helping them to identify what they can do to bring about change. Further, nurses can provide patients with information on how to develop or enhance their problem‐solving skills. However, within the healthcare context, many situations or difficulties that provoke anxiety are not changeable or controllable by individuals, so attempting to bring about change can lead to frustration or an experience of failure.
NICE ([205]) promotes a stepped‐care approach to managing anxiety, with psychological interventions tried before pharmacotherapy. People can choose between ‘individual non‐facilitated self‐help, individual guided self‐help or psycho‐educational groups’ (NICE [205], p.7) and various patient resources are available (see www.ntw.nhs.uk/selfhelp). If these interventions are ineffective, individual high‐intensity psychological interventions, such as cognitive–behavioural therapy and relaxation, may be appropriate (Figure 5.14). Third‐wave cognitive–behavioural therapies – such as mindfulness‐based stress reduction (MBSR), mindfulness‐based cognitive therapy (MBCT), acceptance and commitment therapy (ACT), dialectical behavioural therapy (DBT) and compassion focused therapy (CFT) – have a good evidence base for working with anxiety (Gu et al. [114], Leaviss and Uttley [150], Swain et al. [263]). NICE guidelines advocate patient preference as a factor in the selection of psychological interventions, and some patients prefer more exploratory therapies such as counselling.
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Figure 5.14  Cognitive–behavioural model of anxiety in the context of cancer.

Pre‐procedural considerations

During initial nursing consultations or conversations, it is important that nurses ask patients about any history of psychological or mental health difficulties. This will enable the nurse, where possible, to adapt their approach and minimize anxiety triggers.
Table 5.13  Supporting an anxious person
PrincipleRationale
Be alert to the signs and symptoms of anxiety.Early recognition and intervention may help to prevent worsening of symptoms. E
Encourage the patient to talk about the source of their anxiety if they can. Work openly to explore worries, information requirements and treatment options.Patients may gain some benefit from expressing their concerns and being heard. E
Listen and offer tailored information, but only when the patient has expressed all their concerns. Gentle challenging of misunderstandings about treatment, processes or outcomes may be beneficial if such misunderstandings are the source of the anxiety.Information about a procedure, particularly an operation, can reduce anxiety and improve outcomes (Nordahl et al. [213], R ; Scott [252], R ).
If the patient does not know why they are feeling anxious, encourage them to describe what is happening in their body, when it started, what makes it worse and what makes it better.The patient will feel listened to and less alone, which may increase their sense of security and therefore reduce anxiety. E
Ask the patient whether they have had the feelings before. What has helped previously (coping mechanisms) and what do they think may help this time?This encourages the patient to take control and apply their own coping mechanisms. E
Listen to and incorporate individual needs and preferences to promote informed decision making about treatment and care.If people feel in control, they are likely to feel less worried (NICE [205], C ).

Psychological support

Managing hyperventilation

Managing acute anxiety (including panic attacks) can help to avoid the development of a panic disorder or generalized anxiety disorder. Nurses can support patients to avoid anxiety attacks by taking time to talk through issues. If the anxiety has progressed further and the patient is experiencing the warning signs that they are on the verge of hyperventilation, it is helpful to do the following (adapted from Powell [226]):
  • Remind them that the symptoms they are feeling are not harmful even though they are uncomfortable.
  • Help them to actively release tension in their upper body by encouraging them to sit up and drop their shoulders in a sideways widening direction. This makes hyperventilation more difficult since the chest and diaphragm muscles are stretched outwards.
  • Prompt them to breathe slowly – for example, in to a count of four and out to a count of six. During the in‐breath the sympathetic nervous system is activated and during the out‐breath the parasympathetic nervous system is activated so it is helpful to have a longer out‐breath. The longer, slower out‐breath and its activation of the parasympathetic nervous system help to counteract the sympathetic nervous system, which is responsible for the fight‐or‐flight response, which is activated when a person is anxious and is physiologically responsible for hyperventilation. Slowing down your own breathing can help to model slow breathing to the patient.
Table 5.14  Supporting a person having a panic attack
PrincipleRationale
Firstly, exclude any physical reasons for the patient's distress, such as an acute angina episode or asthma attack.If the symptoms of a panic attack have a physical cause, management needs to be instigated as soon as possible. E
Remain calm and stay with the patient. Ask them about their history of anxiety or panic attacks.The patient will not be reassured by others reacting with tension or anxiety about the situation. E
Maintain eye contact with the patient.This helps the patient to be connected to reality and engage with your attempts to support them. Some patients may be reassured by physical touch, but assess each individual for appropriateness. E
Guide the patient to breathe deeply and slowly, demonstrating where necessary.This gives the patient an activity to concentrate on and may help to normalize any carbon dioxide and oxygen blood imbalance. E

The rebreathing technique

The rebreathing technique involves the patient rebreathing the air they have just breathed out (Box 5.10, Figure 5.15). This air is high in carbon dioxide so has less oxygen. This means that there will be a lower amount of oxygen in the blood, thus activating the parasympathetic nervous system and promoting relaxation (Blake and Ledger [20]).
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Figure 5.15  Hand position for rebreathing technique.
Box 5.10
Rebreathing technique: instructions for a patient
  1. Make a mask of your hands. Put them over your nose and mouth and keep them there (see Figure 5.15).
  2. Breathe in and out through your nose.
  3. Breathe in your own exhaled air through your nose.
  4. Breathe out hard through your mouth.
This should be done slowly, without holding your breath. Repeat steps 2–4 four or five times but no more. Remain calm and relaxed throughout.
Source: Adapted from Powell ([226]) with permission of Speechmark.

Further support

After the panic attack, it is important to reflect with the patient about what happened and try to identify any triggers. Explanation and education about physiological responses can help to show the patient the importance of slowing their breathing, which will in turn give them a sense of control.
If the panic attacks continue or if the patient has a history of anxiety, then management could include a referral for psychological support (with consent). Medication may be indicated after assessment (NICE [205]).

Pharmacological support

Psychological therapies are the first‐line treatment for anxiety problems, but pharmacological treatments may be introduced alongside psychological interventions for more severe cases.
Anxiety disorders include:
  • generalized anxiety disorder (GAD)
  • panic disorder
  • phobias
  • post‐traumatic stress disorder (PTSD)
  • obsessive compulsive disorder (OCD).
Benzodiazepines are very effective in providing short‐term relief from anxiety of all types but are not recommended for long‐term use; the Royal College of Psychiatrists recommends that usage does not exceed four weeks, stating that ‘around 4 in every 10 people who take them every day for more than 6 weeks will become addicted’ (RCPsych [236]). The most commonly used benzodiazepine for immediate relief is lorazepam (a rapidly acting benzodiazepine with a short half‐life). Longer acting benzodiazepines such as diazepam can be used as adjuncts to antidepressants to minimize anxiety, which can occur when starting antidepressant treatment.
Antidepressants are the first‐line psychotropic treatment for the following anxiety disorders: GAD, panic disorder and phobias. Among these, selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants are recommended by NICE ([205]). Serotonin–norepinephrine reuptake inhibitors (SNRIs, e.g. venlafaxine) and pregabalin may be considered as alternative initial treatments if SSRIs are judged to be unsuitable.
Other antidepressants, such as trazadone as well as specific anxiolytic drugs such as buspirone, are sometimes effective for treating anxiety. Antipsychotics such as quetiapine and antihistamines such as promethazine may also be used.
Benzodiazepines, antipsychotics and sedating antihistamines are associated with poor long‐term outcomes, and pharmacological interventions should consist of either tricyclic or SSRI antidepressant medication (NICE [205]).
Nurses have an important role in exploring with the patient any concerns they may have about taking an anxiolytic. The patient should be given all the necessary information regarding the optimum time to take the medication and the expected length of time before any therapeutic effect is likely to become apparent.