Anatomy and physiology

The spinal cord (Figures 10.8 and 10.9) is covered by the meninges; the pia mater is closely applied to the cord and the arachnoid mater lies closely with the outer, tough covering called the dura mater (Tortora and Derrickson [177]). The epidural space lies outside all three membranes, encasing the spinal cord between the spinal dura and ligamentum flavum. The contents of the epidural space include a rich venous plexus, spinal arterioles, lymphatics and extradural fat.
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Figure 10.8  Gross anatomy of the spinal cord. (a) Anterior view and transverse section through the spinal cord. (b) Transverse section of the spinal cord within a cervical vertebra. Source: Reproduced from Tortora and Derrickson ([177]) with permission of John Wiley & Sons.
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Figure 10.9  Branches of a typical spinal nerve, shown in cross‐section through the thoracic portion of the spinal cord: transverse section. Source: Reproduced from Tortora and Derrickson ([177]) with permission of John Wiley & Sons.
The intrathecal space (also termed the subarachnoid space) lies between the arachnoid mater and pia mater and contains the CSF (Tortora and Derrickson [177]). There are 31 pairs of spinal nerves of varying size that pass out through the intervertebral foramina between each vertebra (Tortora and Derrickson [177]). There are two main groups of nerve fibres:
  • Myelinated: myelin is a thin, fatty sheath that protects and insulates the nerve fibres and prevents impulses from being transmitted to adjacent fibres.
  • Unmyelinated: these are delicate fibres that are more susceptible to hypoxia and toxins than myelinated fibres.
The spinal nerves are each composed of a posterior and an anterior root, which join to form the nerve:
  • Posterior root: this transmits ascending sensory impulses from the periphery to the spinal cord.
  • Anterior root: this transmits descending motor impulses from the spinal cord to the periphery by means of its corresponding spinal nerve (Gélinas and Arbour [65]).
Specific skin surface areas are supplied or innervated by each of the spinal nerves. These skin areas are known as ‘dermatomes’ (Figure 10.10).
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Figure 10.10  Distribution of dermatomes.