Anaesthesia

Definition

Intraoperative care is the physical and psychological care given to the patient in the anaesthetic room and operating theatre, prior to their transfer to the post‐anaesthetic care unit. General anaesthesia is usually described as a triad of components that include hypnosis (sleep), analgesia and muscle relaxation.

Evidence‐based approaches

In the anaesthetic room, patients are admitted and checked into the operating suite. The patient is normally transferred (already anaesthetized) into the theatre on a trolley and moved across to the operating table. For some life‐threatening emergency surgery (e.g. ruptured abdominal aortic aneurysm repair), it may be preferable to induce anaesthesia inside the operating theatre with the patient already positioned on the operating table (Leonard and Thompson [98]). A crucial role of the anaesthetic nurse is to support the patient, who is often frightened or anxious due to the unfamiliar, often intimidating environment and apprehensive about both the anaesthesia and the impending surgery (Turunen et al. [205]).
The patient should be carefully checked by the anaesthetist and an anaesthetic practitioner with reference to the ‘Sign In’ portion of the WHO Surgical Safety Checklist (WHO [225]). The patient should be comfortably positioned on a trolley or an operating table with the relevant monitoring devices attached (i.e. ECG leads, blood pressure cuff and pulse oximeter) (AAGBI [5]).
The patient may undergo surgery under general anaesthesia, regional anaesthesia or sedation; they may also have both general and regional anaesthesia. Depending on the nature of the surgery and the patient's co‐morbidities, the anaesthetist may require additional invasive monitoring, such as large‐bore intravenous cannula, arterial line or central venous catheter. After induction of general anaesthesia or performance of regional anaesthesia, and with the patient's cardiorespiratory stability ensured, the patient is carefully transferred to the operating table.
Depending on the nature of the surgery, the patient's position may need to be altered (e.g. moved into the prone or lateral position). Meticulous care of the patient's eyes, skin, joints and nerves must be taken during this positioning and throughout the surgery to avoid complications associated with prolonged immobility. The ‘Time Out’ portion of the WHO Surgical Safety Checklist (WHO [225]) is then completed before commencing the surgical procedure. Nursing activities during the intraoperative period are focused on patient safety, ensuring surgical swab counts are managed safely in accordance with the recommended safety practice, facilitating the procedure and adherence to infection control recommendations. It is then mandatory to complete the ‘Sign Out’ portion of the WHO Surgical Safety Checklist (WHO [225]) to confirm that all surgical counts are correct and to ensure any specific post‐operative concerns from the surgical and anaesthetic team are relayed to the post‐operative nursing care team.

General anaesthesia

The proportion of each of the three components of general anaesthesia (hypnosis/sleep, analgesia and muscle relaxation) may vary according to the surgery. For example, modern muscle relaxants, which emerged in the 1940s, enable adequate relaxation of the abdomen (for example) without relying on very deep anaesthesia (from a single agent) to achieve the same effect (Simpson et al. [192]). Today, anaesthesia is very safe, and there are very few deaths – less than 1 in 250,000 directly related to anaesthesia (RCoA [173]).

Anticipated patient outcomes

The anticipated patient outcomes of the anaesthesia phase of intraoperative care are:
  • to ensure that the patient understands what will happen in the operating theatre in order to minimize anxiety
  • to ensure that the patient has the correct surgery for which the consent form was signed
  • to ensure patient safety at all times and minimize post‐operative complications by:
    • giving the required care for the unconscious patient
    • ensuring injury is not sustained from hazards associated with the use of swabs, needles, instruments, diathermy and power tools
    • minimizing post‐operative problems associated with patient positioning, such as nerve or tissue damage
    • maintaining asepsis during surgical procedures to reduce the risk of post‐operative wound infection in accordance with hospital policies on infection control.

Clinical governance

The WHO Surgical Safety Checklist (WHO [225]) is a structured aid used to enhance communication and improve safety within surgery. It was first implemented in 2008 and is mandated in many countries, including the UK. The aim of the checklist is to decrease the numbers of errors and adverse events, and increase teamwork and communication in surgery. The checklist comprises three parts: before induction of anaesthesia (‘Sign In’), before skin incision (‘Time Out’) and before the patient leaves the operating room (‘Sign Out’) (Figure 16.14).
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Figure 16.14  The World Health Organization's Surgical Safety Checklist. Source: Reproduced from WHO ([225]) with permission of the World Health Organization.

Pre‐procedural considerations

Pharmacological support

Prior to commencing anaesthesia, the patient is assessed by the anaesthetist. The type of anaesthetic administered will depend on multiple factors, including co‐morbidities, the age and risks of the patient, the nature of the planned surgery, and the patient's and clinician's preferences. However, the following components are usually included.

Analgesia

This is an effective form of pain relief and is essential in the post‐operative period. Analgesic drugs are given intravenously intraoperatively in anticipation of post‐operative requirements. Commonly used drugs include paracetamol, non‐steroidal anti‐inflammatory drugs, opioids such as fentanyl and morphine, and ketamine. Peripheral nerve blockade using local anaesthetic agents (regional anaesthesia) is also widely used to render the operative site numb and pain free. Surgeons may also infiltrate local anaesthetic into wounds to help with post‐operative analgesia.

Antiemetics

Antiemetics are given with analgesia. Various factors influence the incidence of post‐operative nausea and vomiting, and these may be pre‐existing patient factors, surgical factors and anaesthetic‐related factors. Antiemetic drugs have various mechanisms of action: commonly used agents include ondansetron, cyclizine, prochlorperazine and dexamethasone. The anaesthetic technique can also be adapted to reduce the risk of post‐operative nausea and vomiting. The use of total intravenous anaesthesia using drugs such as propofol and remifentanil is associated with lower incidence of post‐operative nausea and vomiting compared with volatile anaesthesia. Another anaesthetic alternative may be to perform the surgery under regional or local anaesthesia, thus avoiding the need for general anaesthesia completely.

Induction agents

Induction agents are drugs that induce unconsciousness. The most commonly used intravenous agent is propofol, a short‐acting drug that can also be used to maintain anaesthesia as an intravenous infusion in total intravenous anaesthesia. Other intravenous induction agents include the barbiturate thiopentone, etomidate and ketamine (each of which can also be administered intramuscularly). General anaesthesia may also be induced through inhalation of volatile anaesthetic agents, such as sevoflurane.

Inhalational agents

After induction, anaesthesia can be maintained by either inhalational anaesthetic agents or intravenous infusion (e.g. propofol). Examples of modern inhalational agents are sevoflurane, desflurane and isoflurane. These volatile gases are administered through vaporizers, which are integrated into modern anaesthetic machines (Figure 16.15).
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Figure 16.15  Anaesthetic machine.

Muscle relaxants

Drugs that cause relaxation of the skeletal muscles (temporary paralysis) may be administered intravenously when the patient is unconscious in order to aid tracheal intubation and/or to improve conditions for the surgeon during the operation. Commonly used relaxants are suxamethonium, atracurium, vecuronium and rocuronium. The degree of muscle paralysis must be monitored with a peripheral nerve stimulator.

Specific patient preparation

When the patient arrives in the anaesthetic room, their identity is checked and the safety checklist is completed. At this point, consent is verified with the patient in order to confirm the planned operation. This should include the correct side of the body to be operated on, if relevant. A competent anaesthetic assistant must be present, and the surgeon must be ready. This completes the final phase of the pre‐anaesthetic checklist.