Chapter 20: Diagnostic investigations
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20.6 Flexible cystoscopy with bladder biopsy
Essential equipment
- Patient trolley
- Incontinence sheet
- Flexible cystoscope (optical/video)
- Urology sterile pack as determined by local practice, including sterile gauze and sterile forceps
- Procedure trolley
- Non‐sterile gloves
- Apron
- Sterile gloves
- Sterile gown
- Sterile drapes
- Chlorhexidine cleansing solution or similar according to local guidelines
- 1 litre bag of sterile water
- Fluid giving set
- Biopsy forceps
- Specimen container with formalin
- Cystodiathermy checked and in working order
Medicinal products
- 2% lidocaine gel (topically into urethra)
- Intravesical sodium chloride 0.9%
Pre‐procedure
ActionRationale
- 1.Check the environment and equipment to ensure that everything is properly prepared for the procedure, including that the irrigation is attached and run through the scope, and awareness of the location and availability of emergency equipment.
- 2.Ask assistant to set up trolley with sterile urology pack and prepare scope.
- 3.Read the patient's notes, referral letter, patient history and relevant investigation results and identify any special instructions, investigations or items for which you need to seek advice prior to the procedure, including any metal prosthesis.
- 4.Ensure that pre‐procedure criteria have been met:
- urine sample tested for infection, the results interpreted and a sample sent for further analysis if required
- urine cytology obtained if required
- pre‐procedure medication has been taken as required, such as prophylactic antibiotic
- patient has emptied bladder
- observations within normal limits
- check medications and anticoagulation have been reviewed or withheld.
- 5.Accurately identify the patient and introduce yourself and any colleagues present to the patient.
- 6.Assess the patient's suitability for the procedure, including any changes to health since referral, medication or allergy status, and seek advice or refer if necessary.
- 7.Explain the procedure and potential complications to the patient and accurately answer any questions at a level and pace that is appropriate to:
- their level of understanding
- their culture and background
- their preferred way of communicating their needs.
- 8.Ensure the patient's informed consent to the procedure has been given and, if not, obtain it.
- 9.Ensure that the cystoscope is diathermy compatible.
- 10.Ensure that irrigation fluid is diathermy compatible, for example 1.5% glycine or normal saline.
- 11.Ask the patient to remove any metal jewellery or to cover with non‐conductive tape.
- 12.Ask the patient to remove clothing below the waist. Offer a gown to cover the patient.
- 13.Assist the patient to position themselves onto an incontinence sheet on the trolley correctly for the procedure (supine), respecting their dignity and ensuring their comfort within the constraints of the procedure. Males lay flat and females with legs apart.
- 14.Ensure the patient is not in contact with any metal surface.
- 15.Prepare the area for the diathermy plate by shaving excessive hair (usually the patient's thigh) while avoiding bony prominences, wet skin, scar tissue, metal prosthesis or tattoos.
- 16.Wash hands with soap and water and dry, followed by alcohol rub, and apply non‐sterile gloves and apron.
- 17.Identify, clean with cleansing solution such as chlorhexidine solution and examine the urethral orifice and surrounding area. In females open the labia, and in males retract the foreskin.
- 18.Insert local anaesthetic gel topically into the urethra, leaving for 5–10 minutes.
- 19.Remove gloves and apron and discard in clinical waste.
- 20.Wash hands with soap and water, followed by alcohol rub, and apply sterile gloves and gown.
- 21.Apply sterile drape over patient's lower body.
Procedure
- 22.Maintain communication with the patient throughout the procedure, monitor and respond to any questions or needs.
- 23.Ensure the labia are held open in females or the foreskin is retracted in males. This should be done either by an assistant or with your non‐dominant hand.
- 24.Introduce the cystoscope into the urethra and advance it gently under direct vision using deflection (Action figure 19a) and inflection (Action figure 19b) (change in angle) of the tip to avoid trauma to the urethral wall and ensure that the correct irrigation fluid is running (normal saline if washings are required to preserve the cells).
- 25.If insertion is difficult, or problems occur, seek advice or decide to terminate the procedure and record your findings.To maintain patient safety. E
- 26.Fill bladder sufficiently with irrigation fluid to facilitate systematic examination of the internal structure of the bladder and to identify anatomical landmarks using tip deflection and inflection, instrument rotation and gentle advancement and withdrawal of the cystoscope.
- 27.Identify all abnormal lesions or bleeding areas throughout the examination. Record images throughout procedure using the video stack, external printer or software connected to the stack and scope.
- 28.Improve visualization, if necessary, by aspirating fluids from the bladder.
- 29.Select the diathermy compatible biopsy forceps and ensure they are in working order.
- 30.Insert biopsy forceps through the channel of the cystoscope using dominant hand while keeping the cystoscope tip in the straight position.
- 31.Visualize the biopsy forceps as they enter the bladder and field of vision.
- 32.Use the cystoscope controls to orientate the biopsy forceps over the tissue to be sampled.
- 33.Open the jaws of the biopsy forceps or instruct an assistant to operate the biopsy forceps.To ensure grasping forceps are operated correctly and safely. E
- 34.Close the biopsy forceps jaws, taking an adequate tissue sample.
- 35.While biopsy forceps are closed, pull sharply from the bladder tissue.
- 36.Withdraw the biopsy forceps via the cystoscope channel while keeping the jaws closed, or instruct the assistant to do so.
- 37.Deposit all of the tissue sample into the specimen pot or instruct the assistant, making sure the biopsy forceps do not touch the sterile pot.
- 38.Clean the forceps between each sample in sodium chloride 0.9%.To ensure biopsy forceps are clean and ready for additional sampling. E
- 39.Visualize biopsy sites for excessive bleeding and perform cystodiathermy if required (see Procedure guideline 20.7 Cystoscopy with APC/cystodiathermy.
- 40.Repeat steps 32–39 for subsequent samples.
- 41.Once complete, fully withdraw cystoscope, maintaining irrigation until withdrawal of cystoscope is almost complete.To ensure cystoscope is fully withdrawn. E
Post‐procedure
- 42.Reassure patient that the examination has been completed.To maintain patient comfort and safety. E
- 43.Assist the patient to reposition, wipe surplus lubricant and dry.To maintain patient comfort and safety. E
- 44.Remove gloves and dispose of all used single‐use equipment. Return cystoscope for washing according to local guidelines.
- 45.Label specimens and send to laboratory for histopathological analysis.
- 46.Ask the patient to pass urine before leaving the department.