Only negative‐pressure rooms or positive‐pressure lobbied rooms (which all have sufficient extraction) are to be used where ribavirin is administered via a nebulizer. During nebulized administration of the drug, entry to the room should be limited as far as is practically possible. A warning sign ‘Respiratory Isolation: Do Not Enter: Ribavirin Administration In Progress’ must be placed on the patient's door during the time that the Aiolos nebulizer is in operation to ensure that staff and visitors do not unknowingly enter the room. Signs should be available from the infection control team. If an appropriate room is not available, consideration should be given to delaying the use of nebulized ribavirin, and intravenous or oral administration may be considered.