Chapter 23: Administration of systemic anticancer therapies
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23.1 Cytotoxic spillage management
Essential equipment
- Two plastic overshoes
- Two disposable armlets
- Two clinical waste bags
- Two pairs of disposable non‐sterile vinyl or nitrile gloves
- Goggles (non‐disposable): EN 166‐8
- Particulate respirator mask
- Plastic apron
- Long‐sleeved gown
- Paper towels
- Plastic bucket
- Copy of spillage procedure
Pre‐procedure
ActionRationale
- 1.Act immediately. Assess the level of exposure of any individual and isolate them from the spill.
- 2.Collect spillage kit.
- 3.Put on both pairs of gloves, goggles and a gown and then a disposable plastic apron over the gown (see Action figure 3).
- If there is visible powder spill, put on a good‐quality particulate respirator mask.
- If spillage is on the floor, put on overshoes.
Procedure
- 4.Wipe up powder spillage quickly with well‐dampened paper towels, starting at the outer edge of the spill area and working in a circular motion towards the middle to contain spill (Weinstein and Hagle [265]), and dispose of the towels as ‘high‐risk’ waste.
- 5.Mop up liquids that have been spilled on a hard surface with paper towels, starting at the outer edge of the spill area and working in a circular motion towards the middle to contain spill (Ferguson and Wright [74]), and dispose of the towels as ‘high‐risk’ waste.To prevent spread of contamination to a wider area. To protect others and ensure safe disposal by incineration (DH 2012, C).
- 6.Wash hard surfaces at least twice with copious amounts of cold, soapy water and dry with paper towels. The floor should then be given a routine clean as soon afterwards as possible. If spillage has occurred on a carpet, it will require cleaning as soon as possible.
- If spillage is on clothing, remove it as soon as possible and treat as ‘soiled linen’.
- If spillage has penetrated clothing, wash contaminated skin liberally with soap and cold water.
- If spillage is on bedlinen, put on gloves and an apron, change it immediately and treat as ‘soiled linen’.
- If an accident or spillage involving direct skin contact occurs, the area should be washed thoroughly with soapy water as soon as possible. In the event of a cytotoxic splash to the eye, irrigate thoroughly with 0.9% sodium chloride or tap water for at least 15 minutes.
To remove residual contamination. E
Post‐procedure
- 7.Any accident or spillage by nursing staff involving direct skin contact with a cytotoxic drug must be reported to the occupational health department and manager as soon as possible after the first aid is performed and appropriate documentation completed (see Box 23.2).