Chapter 23: Administration of systemic anticancer therapies
Skip chapter table of contents and go to main content
23.6 Cytotoxic therapy: intramuscular administration of cytotoxic drugs (Z‐track)
Essential equipment
- Alcohol swab
- Needle
- Syringe containing prepared intramuscular (IM) medication
- Non‐sterile gloves
- Plastic apron
Pre‐procedure
ActionRationale
- 1.Explain and discuss the procedure with the patient.
- 2.Consult the patient's prescription sheet, and ascertain the following:
- Drug.
- Dose.
- Date and time of administration.
- Route and method of administration.
- Diluent as appropriate.
- Validity of prescription.
- Signature of doctor.
- Allergy status.
Procedure
- 3.Assist the patient into the required position.
- 4.Put on apron and gloves.
- 5.Remove the appropriate garment to expose the injection site.
- 6.Assess the injection site for signs of inflammation, oedema, infection and skin lesions.
- 7.Clean the injection site with a swab saturated with isopropyl alcohol 70% for 30 seconds and allow to dry for 30 seconds.
- 8.With the non‐dominant hand, pull the skin 2–3 cm sideways or downwards from the injection site.
- 9.Holding the syringe in the dominant hand like a dart, inform the patient and quickly plunge the needle at an angle of 90° into the skin until about 1 cm of the needle is left showing.
- 10.Pull back the plunger. If no blood is aspirated, depress the plunger at approximately 1 mL every 10 seconds and inject the drug slowly. If blood appears, withdraw the needle completely, replace it and begin again. Explain to the patient what has occurred.
- 11.Wait 10 seconds before withdrawing the needle.
- 12.Withdraw the needle rapidly and release the tension on the skin but do not massage the site.
- 13.Apply gentle pressure to any bleeding point and then apply a small plaster over the puncture site.
Post‐procedure
- 14.Ensure that all sharps and non‐sharps waste are disposed of safely and in accordance with locally approved procedures, for example put sharps into sharps bin and syringes into cytotoxic clinical waste bag.
- 15.Record the administration on appropriate charts.