Chapter 23: Administration of systemic anticancer therapies
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23.8 Cytotoxic therapy: intraventricular administration of cytotoxic drugs via an intraventricular access device (Ommaya reservoir)
Essential equipment
- 25 G winged infusion devices or small non‐coring needle
- Sterile dressing pack
- Cleaning solution
- Pre‐prepared chemotherapy
- Three‐way tap
Pre‐procedure
ActionRationale
- 1.Explain and discuss the procedure with the patient.
- 2.Consult the patient's prescription sheet, and ascertain the following:
- Drug.
- Dose.
- Date and time of administration.
- Route and method of administration.
- Diluent as appropriate.
- Validity of prescription.
- Signature of doctor.
- Allergy status.
- 3.Position the patient comfortably.To gain access to the site. E
- 4.Apply apron and necessary personal protective equipment, for example gloves, goggles.
- 5.Wash hands with antibacterial soap.
- 6.Open sterile pack and pour antiseptic liquid into gallipot.To prepare the area. E
- 7.Open intrathecal chemotherapy drugs by cutting plastic pack and place on sterile field.To gain access to chemotherapy. E
- 8.Open non‐coring winged infusion device and connect a three‐way tap to the tubing.To prepare the equipment. E
- 9.Clean hands with alcohol gel.
Procedure
- 10.Locate the reservoir by slightly depressing the dome several times. There should be free flow of CSF from the ventricle into the dome.
- 11.Wash hands with antibacterial handwash and put on sterile gloves.
- 12.Prepare the skin by cleaning the site.
- 13.Using the 25 G needle, access the reservoir and remove a small amount of CSF equal to the amount of drug to be instilled.
- 14.Connect syringe containing chemotherapy to three‐way tap and inject slowly. No resistance should be felt.
- 15.Compress and release the dome after all medication is given.
- 16.The reservoir can now be flushed with the CSF removed at the start of the procedure. Do not flush with 0.9% sodium chloride or heparin.
- 17.Remove the needle and apply pressure with gauze.To prevent leakage of CSF or chemotherapy. E
- 18.Dispose of sharps and syringe in a purple‐lidded sharps container.To maintain a safe environment. E
- 19.Once CSF stops leaking, apply a small gauze dressing and tape.
Post‐procedure
- 20.Assist patient in repositioning if required.To maintain comfort. E
- 21.Dispose of equipment in appropriate waste bags.To maintain a safe environment. E
- 22.Wash and dry hands.
- 23.Document chemotherapy administration on the prescription chart.
- 24.Monitor the patient for any side‐effects of the drugs and check reservoir site for any leaks.