Chapter 24: Radionuclide therapy
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Pre‐procedural considerations for gynaecological brachytherapy
Equipment
Equipment should be kept to a minimum. It must be checked to ensure that it is in working order, as maintenance staff will only be allowed into the room in exceptional circumstances.
Bedlinen and disposable items (e.g. gloves, aprons, catheter packs, sanitary towels) should be kept in a utility room or anteroom along with the patient's treatment chart and a radiation monitor.
Specific patient preparations
The patient is usually admitted 12–48 hours before the procedure so that any pre‐anaesthetic investigations may be performed. Full bowel preparation with a low‐residue diet will reduce the chance of the patient having a bowel action while the sources are in place to help reduce the risk of sources being dislodged. If patients present with pre‐existing diarrhoea caused by previous radiotherapy on admission, regular antidiarrhoea medication should be prescribed and administered before and during the application of the sources. A full explanation should be given about the method and mode of treatment, possible side‐effects, radiation protection issues and obtaining informed consent. The patient should be encouraged to have a bath before any pre‐medication is administered.
LDR brachytherapy often follows 5 weeks of external beam radiotherapy (EBRT) to the pelvis (Petereit et al. [56]). Patients may embark on treatment already experiencing many symptoms, which are likely to include radiation‐induced enteritis, nausea, fatigue, pain and skin reactions. Management of these symptoms is essential to ensure the safe and effective use of LDR brachytherapy.
Prior to the procedure, patients should also be prepared for the number of applicators to be inserted, dependent on previous treatment. A urinary catheter will be inserted because of the restriction around movement during the treatment. Small but significant aspects to highlight to the patient at this pre‐assessment meeting include the noises made by the Selectron system, especially when sources are being transferred in and out of the applicators, that connection to the Selectron unit is with flexible plastic tubes, and informing all patients that this treatment will only enable them to lie in a semi‐recumbent position.
A maximum of two pillows can be used to support the head whilst maintaining the pelvis in roughly the same position, ensuring no significant movement of the applicators. Where practicable, the patient should be closely monitored during treatment using closed‐circuit television camera, telephone and/or intercom access for the patient as well as a nurse call system; all provide further reassurance for patients undergoing this treatment.
Personal items
Nurses should be sensitive to the psychological implications for patients confined in isolation and receiving radiation treatment. Although patients may want to bring some personal belongings with them, they should be advised to keep these to a minimum.
Procedure guideline 24.9
Sealed source therapy: caesium sources (manual or afterloading): patient care
Procedure guideline 24.10
Sealed source therapy: low dose rate Selectron treatment
Procedure guideline 24.11
Sealed source therapy: Selectron applicator removal
Problem | Cause | Prevention | Action |
---|---|---|---|
Patient removes the applicators herself. | Possible causes can be post‐anaesthetic, infection and/or isolation issues. | Clear explanation to the patient about the problems of removing the applicators. | Check the room for any sources that may have escaped, using a contamination monitor; sources that have escaped should be placed in lead pots using long‐handled forceps and the physics department notified. |
Remove applicators completely if partially removed as per instructions above. In the confused patient, this is a two‐nurse procedure. | |||
Applicator is partially dislodged. | Patient may have moved too much or too vigorously. | Explanation to patient about amount of movement allowed. | Interrupt treatment and inform physicist and radiotherapist; the applicator may have to be removed as in Procedure guideline 24.11. |
Alarm sounding at nurse station. | Treatment has been interrupted and inadvertently left off. | Check all settings when leaving the patient. | Check the patient is not requiring any nursing intervention and then check the patient is unattended; if unattended, recommence treatment. |
Sources are not transferred to the applicators. | Incorrect coupling or loose connection. | Check all connections. | Check print‐out to identify which channel is at fault; tighten appropriate coupling device. If not resolved, contact physics department. |
Alarm activated at remote control unit. | Failure in the system. | Check Selectron is kept maintained. | Check the error code on the print‐out with the Selectron user's manual.
Rectify as indicated in the manual or seek technical assistance from the physics department. |
Pellets stuck in the applicator or transfer tubing. | A damaged or kinked catheter tubing. | Check the catheter tubing prior to use. | A risk assessment to be completed regarding the likelihood of this occurrence (HSE [29]). Inform the patient of the problem and contact physics department and the medical team. |