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Research Explanation

  • E:  Clinical experience
  • P:  Patient
  • C:  Context
  • R1 (a):  Systematic reviews of randomized controlled trials (RCTs)
  • R1 (b):  Individual RCTs with narrow confidence limits
  • R2 (a):  Systematic reviews of cohort studies
  • R2 (b):  Individual cohort studies and low quality RCTs
  • R3 (a):  Systematic reviews of case‐controlled studies
  • R3 (b):  Case‐controlled studies
  • R4:  Case series and poor quality cohort and case‐controlled studies
  • R5:  Expert opinion
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